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5Ohybrid-indica
Hybrid-IndicaModernTHC-Dominantafternoon

501st OG

25.1%

THC

Top flavors

earthyspicycitrus
CalmingEnergizing

501st OG effects are mostly calming.

Low THCHigh THC

501st OG potency is higher THC than average.

501st OG is a modern hybrid-indica strain developed from the genetics of Rare Dankness #1. This variety is cultivated for its high-yield potential and requires moderate skill throughout its 58-day flowering cycle. It is suitable for both indoor and outdoor environments, making it a versatile choice for growers seeking reliable production.

The chemical profile of 501st OG is defined by a complex arrangement of terpenes, led by myrcene, caryophyllene, and limonene. Humulene, linalool, and pinene offer secondary aromatic depth, while the profile concludes with nuanced traces of beta-pinene, bisabolol, and ocimene. This THC-dominant cultivar presents a therapeutic sensory experience reflected through the precise interplay of these nine specific compounds.

Upon consumption, users typically experience states characterized by relaxation, calm, and focus. These effects make the strain particularly suitable for managing pain, stress, and sleep difficulties. The genetic impact of 501st OG is evidenced by its notable offspring, which include OG Magnum, Orange Headrush, Platinum Purple Hulk, Purple Sherb, Shaq Fu, and Street T.

Terpene Profile

Synergies (+) and conflicts (−) are relative to each other within this profile.

myrcene ~60%caryophyllene ~28%limonene ~12%
TerpeneShare
myrcene~60%
caryophyllene~28%
limonene~12%

Research notes below describe isolated terpene mechanisms and early findings. They do not guarantee effects from this strain and are not medical advice.

~60%

earthy

●●●○

relaxingsolosleep
+ linalool+ caryophyllene+ nerolidol− pinene− terpinolene

Russo 2011: naloxone-sensitive analgesia, potentiates barbiturate sleep; dominant sedating terpenoid; blocks hepatic carcinogenesis by aflatoxin.

~28%

spicy

●●○○

relaxingsocialfocus
+ myrcene+ humulene+ limonene

Russo 2011: only terpene that is a selective full CB2 agonist (100 nM); Gertsch et al. 2008: acts as dietary cannabinoid; unique anti-inflammatory and gastric cytoprotective properties.

~12%

citrus

●●○○

socialcreativefocus
+ linalool+ caryophyllene+ pinene− myrcene− nerolidol

Russo 2011: increases serotonin in prefrontal cortex + dopamine in hippocampus via 5-HT1A; Johns Hopkins 2024: significantly reduced anxiety vs THC alone.

Effects

Reported effects — derived from terpene chemistry and cannabinoid profile.

◎

relaxed

evening

Primary endpoint of myrcene+linalool sedating combinations; GABA modulation is the dominant mechanistic driver.

⊕

focused

morning

Pinene acetylcholinesterase inhibition (IC50 0.44 mM per Russo 2011) sustains acetylcholine; counteracts THC-induced short-term memory deficits.

Genetic Profile

Indica-dominant

■ Indica 70%■ Sativa 30%

Primarily indica with sativa influence. Relaxing body with some cerebral lift.

THC-Dominant

High THC, trace CBD. Psychoactive. Full CB1 agonism — euphoria, appetite, analgesia.

Genealogy

Parentage, ancestry, and genetic relatives of 501st OG.

View full lineage tree →

Composite Traits

Use caution if

appetite-boostdaytime-productivitymorning-use

Where to buy 501st OG

No verified dispensaries on file — find it on Leafly.

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⊕

What would 501st OG × ? produce?

Predict the terpene profile, effects, and growing traits of a cross. Our gene weaver engine votes on dominant traits from both parents.

Build a cross with 501st OG →

Similar strains

Same primary terpene with overlapping effects.

Frequently Asked Questions

Is 501st OG indica or sativa?

501st OG is modeled here as a indica-dominant (primarily indica with sativa influence).

What terpene is dominant in 501st OG?

Myrcene is shown as the dominant terpene at approximately ~60%. Caryophyllene follows as the secondary terpene.

Is 501st OG good for daytime use?

501st OG is versatile and works across different times of day depending on dose and individual response.

How accurate is this data?

See the "Data confidence" card in the sidebar. Terpene profiles and effects are chemistry-informed estimates — individual responses depend on phenotype, source, and personal chemistry.