EMhybrid

Eastside Mac

22.8%

THC

Top flavors

citrusspicyfloral
CalmingEnergizing

Eastside Mac effects are mostly energizing.

Low THCHigh THC

Eastside Mac potency is average.

Eastside Mac is a modern hybrid cannabis strain derived from the genetic lineage of Mac 1. Evaluated as a product of intentional breeding, this strain is well-suited for both indoor and outdoor cultivation environments. Growers can expect a moderate level of difficulty throughout the cycle, which concludes with a 63-day flowering period and a high total yield.

The chemical profile of Eastside Mac is defined by a complex arrangement of terpenes, led by limonene, caryophyllene, and linalool. This primary trio is followed by pinene, beta-pinene, humulene, bisabolol, and myrcene. The secondary and tertiary constituents include nerolidol, valencene, caryophyllene-oxide, ocimene, camphene, gamma-terpinene, borneol, eucalyptol, and terpinolene. This specific composition creates the unique aromatic and flavor profile characteristic of this THC-dominant hybrid, which tests at 22.8% THC.

Users of Eastside Mac report effects that are primarily relaxed, happy, and uplifted. These qualities make the strain a frequent choice for managing stress and pain, as well as addressing sleep concerns. Beyond its personal use applications, the strain has demonstrated its utility as a parent in further breeding efforts, with notable offspring such as Eastside Smack and E. Pink St. confirming its influence on a new generation of hybrid genetics.

Terpene Profile

Synergies (+) and conflicts (−) are relative to each other within this profile.

limonene ~60%caryophyllene ~28%linalool ~12%
TerpeneShare
limonene~60%
caryophyllene~28%
linalool~12%

Research notes below describe isolated terpene mechanisms and early findings. They do not guarantee effects from this strain and are not medical advice.

~60%

citrus

●●○○

Russo 2011: increases serotonin in prefrontal cortex + dopamine in hippocampus via 5-HT1A; Johns Hopkins 2024: significantly reduced anxiety vs THC alone.

~28%

spicy

●●○○

Russo 2011: only terpene that is a selective full CB2 agonist (100 nM); Gertsch et al. 2008: acts as dietary cannabinoid; unique anti-inflammatory and gastric cytoprotective properties.

~12%

floral

●●○○

Russo 2011: local anesthetic equal to procaine; anticonvulsant via glutamate/GABA modulation; reduces morphine tolerance via multisite opioid/GABAergic/cannabinoid action.

Effects

Reported effects — derived from terpene chemistry and cannabinoid profile.

Genetic Profile

Balanced Hybrid

■ Indica 50%■ Sativa 50%

Equal indica and sativa genetics. Balanced body and mind effects.

THC-Dominant

High THC, trace CBD. Psychoactive. Full CB1 agonism — euphoria, appetite, analgesia.

Genealogy

Parentage, ancestry, and genetic relatives of Eastside Mac.

Composite Traits

Use caution if

evening-wind-downdaytime-productivity

Where to buy Eastside Mac

No verified dispensaries on file — find it on Leafly.

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What would Eastside Mac × ? produce?

Predict the terpene profile, effects, and growing traits of a cross. Our gene weaver engine votes on dominant traits from both parents.

Build a cross with Eastside Mac

Similar strains

Same primary terpene with overlapping effects.

Frequently Asked Questions

Is Eastside Mac indica or sativa?

Eastside Mac is modeled here as a balanced hybrid (equal indica and sativa genetics).

What terpene is dominant in Eastside Mac?

Limonene is shown as the dominant terpene at approximately ~60%. Caryophyllene follows as the secondary terpene.

Is Eastside Mac good for daytime use?

Eastside Mac is versatile and works across different times of day depending on dose and individual response.

How accurate is this data?

See the "Data confidence" card in the sidebar. Terpene profiles and effects are chemistry-informed estimates — individual responses depend on phenotype, source, and personal chemistry.