First Lady
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Terpenes
First Lady effects are mostly calming.
First Lady
First Lady is a modern hybrid cannabis strain resulting from the crossing of indica and sativa genetics. Designed by cultivators to achieve a balance of traits, this variety has demonstrated its reach by serving as the genetic foundation for notable offspring such as Giga Brain Auto. Growers looking to include this strain in their garden will find it is of moderate difficulty to cultivate, capable of thriving in both indoor and outdoor environments. With an efficient flowering cycle of 56 days, the plant is recognized for its ability to produce a high yield.
The chemical composition of First Lady is defined by a terpene profile dominated by myrcene, followed by caryophyllene and limonene. These compounds work in concert to establish the strain's aromatic and flavor characteristics. This specific configuration of terpenes supports the overall profile of the plant, influencing how the strain is perceived by the senses during consumption. As a THC-dominant variety, the interplay between these dominant terpenes and the primary cannabinoid profile dictates the nuanced experience of this hybrid.
Users of First Lady frequently report feeling relaxed, happy, and uplifted after consumption. These effects make the strain a suitable candidate for those seeking relief from stress and pain, as well as those looking for assistance with sleep. By combining these functional outcomes with a relatively short flowering time and productive yields, First Lady has secured a functional place in the modern market. Its influence continues to be observed through its documented legacy in newer varieties within the botanical landscape.
Terpene Profile
Synergies (+) and conflicts (−) are relative to each other within this profile.
| Terpene | Share | Character | Likely role |
|---|---|---|---|
| myrcene | ~60% | earthy | relaxing · solo |
| caryophyllene | ~28% | spicy | relaxing · social |
| limonene | ~12% | citrus | social · creative |
Research notes below describe isolated terpene mechanisms and early findings. They do not guarantee effects from this strain and are not medical advice.
Russo 2011: naloxone-sensitive analgesia, potentiates barbiturate sleep; dominant sedating terpenoid; blocks hepatic carcinogenesis by aflatoxin.
~28%
spicy
●●○○
Russo 2011: only terpene that is a selective full CB2 agonist (100 nM); Gertsch et al. 2008: acts as dietary cannabinoid; unique anti-inflammatory and gastric cytoprotective properties.
Russo 2011: increases serotonin in prefrontal cortex + dopamine in hippocampus via 5-HT1A; Johns Hopkins 2024: significantly reduced anxiety vs THC alone.
Effects
Reported effects — derived from terpene chemistry and cannabinoid profile.
relaxed
eveningPrimary endpoint of myrcene+linalool sedating combinations; GABA modulation is the dominant mechanistic driver.
happy
anytimeuplifted
morningLimonene anxiolytic/antidepressant via serotonin elevation in prefrontal cortex (Russo 2011); mood improvement without full euphoria; key for balanced-1-1 profiles.
Genetic Profile
Balanced Hybrid
Equal indica and sativa genetics. Balanced body and mind effects.
THC-Dominant
High THC, trace CBD. Psychoactive. Full CB1 agonism — euphoria, appetite, analgesia.
Genealogy
Parentage, ancestry, and genetic relatives of First Lady.
Siblings
Share parent indica sativa
Offspring — 1 strains bred from First Lady
Composite Traits
Where to buy First Lady
No verified dispensaries on file — find it on Leafly.
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What would First Lady × ? produce?
Predict the terpene profile, effects, and growing traits of a cross. Our gene weaver engine votes on dominant traits from both parents.
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Frequently Asked Questions
Is First Lady indica or sativa?
First Lady is modeled here as a balanced hybrid (equal indica and sativa genetics).
What terpene is dominant in First Lady?
Myrcene is shown as the dominant terpene at approximately ~60%. Caryophyllene follows as the secondary terpene.
Is First Lady good for daytime use?
First Lady is versatile and works across different times of day depending on dose and individual response.
How accurate is this data?
See the "Data confidence" card in the sidebar. Terpene profiles and effects are chemistry-informed estimates — individual responses depend on phenotype, source, and personal chemistry.