Fhybrid-indica
Hybrid-IndicaModernTHC-Dominantevening

Five-O

Top flavors

earthypinesweet
CalmingEnergizing

Five-O effects are mostly calming.

Five-O is a modern hybrid-indica strain derived from Northern Lights #5. As a genetic selection, it is cultivated to thrive in both indoor and outdoor environments, offering a high yield after a flowering period of 58 days. While the cultivation process is rated at a moderate difficulty level, the strain has demonstrated enough stability and desirable traits to serve as a parent for notable offspring, including Cali Miss and Electric Haze.

The chemical profile of Five-O is defined by a complex terpene hierarchy, led by myrcene, pinene, and ocimene. These primary aromatics transition into a secondary base of limonene, caryophyllene, beta-pinene, and linalool, with trace contributions from humulene, guaiol, bisabolol, nerolidol, and camphene. This combination creates a distinct sensory profile, characterized by the interplay between the earthy foundation of myrcene and the sharp, bright top notes contributed by pinene and ocimene.

This THC-dominant cultivar is formulated to produce effects that are primarily relaxed, calm, and focused. These properties make it a functional choice for users seeking relief from pain, stress, or difficulty achieving restful sleep. Beyond its immediate application, the genetic legacy of Five-O continues to shape modern cannabis breeding, as evidenced by the development of its recognized progeny.

Terpene Profile

Synergies (+) and conflicts (−) are relative to each other within this profile.

myrcene ~60%pinene ~28%ocimene ~12%
TerpeneShare
myrcene~60%
pinene~28%
ocimene~12%

Research notes below describe isolated terpene mechanisms and early findings. They do not guarantee effects from this strain and are not medical advice.

~60%

earthy

●●●○

Russo 2011: naloxone-sensitive analgesia, potentiates barbiturate sleep; dominant sedating terpenoid; blocks hepatic carcinogenesis by aflatoxin.

~28%

pine

●●○○

Russo 2011: acetylcholinesterase inhibitor (IC50 0.44 mM) counteracting THC-induced short-term memory deficits; most widely encountered terpenoid in nature; anti-inflammatory via PGE-1.

~12%

sweet

●○○○

Antifungal, antiviral, decongestant; activates CB1/CB2 at 10–60% THC efficacy per Israeli receptor study (NORML 2025); highly volatile (bp 50–66°C); limited clinical data.

Effects

Reported effects — derived from terpene chemistry and cannabinoid profile.

Genetic Profile

Indica-dominant

■ Indica 70%■ Sativa 30%

Primarily indica with sativa influence. Relaxing body with some cerebral lift.

THC-Dominant

High THC, trace CBD. Psychoactive. Full CB1 agonism — euphoria, appetite, analgesia.

Genealogy

Parentage, ancestry, and genetic relatives of Five-O.

Composite Traits

Use caution if

daytime-productivitymorning-useevening-wind-down

Where to buy Five-O

No verified dispensaries on file — find it on Leafly.

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What would Five-O × ? produce?

Predict the terpene profile, effects, and growing traits of a cross. Our gene weaver engine votes on dominant traits from both parents.

Build a cross with Five-O

Similar strains

Same primary terpene with overlapping effects.

Frequently Asked Questions

Is Five-O indica or sativa?

Five-O is modeled here as a indica-dominant (primarily indica with sativa influence).

What terpene is dominant in Five-O?

Myrcene is shown as the dominant terpene at approximately ~60%. Pinene follows as the secondary terpene.

Is Five-O good for daytime use?

Five-O is versatile and works across different times of day depending on dose and individual response.

How accurate is this data?

See the "Data confidence" card in the sidebar. Terpene profiles and effects are chemistry-informed estimates — individual responses depend on phenotype, source, and personal chemistry.