Los Muertos is a modern hybrid whose precise origins remain undocumented, as breeders have not publicly confirmed a comprehensive lineage. While the strain is associated with parentage from Project 4516, the full genetic history of the plant remains thin and currently lacks official documentation or a primary breeder description. This variety is categorized as a modern hybrid and is not a landrace or heritage strain, reflecting the limited historical context surrounding its development.

The chemical profile of Los Muertos is characterized by a complex array of terpenes, led by dominant limonene, followed by caryophyllene, humulene, and myrcene. Secondary and tertiary contributions consist of beta-pinene, linalool, pinene, bisabolol, and terpinolene. This terpene combination suggests an estimated aromatic profile that likely shifts between sharp citrus and deep, earthy spice. Regarding potency, the strain is THC-dominant, with an estimated average of 25.1% THC content, though individual batches may vary.

Users of Los Muertos report feelings of being relaxed, happy, and uplifted. These effects make the strain a common choice for those seeking relief from stress, pain, or difficulty with sleep. The plant is suited for both indoor and outdoor cultivation, requiring a moderate level of grower expertise to reach its potential. With a flowering cycle of 65 days, the strain is capable of producing a high yield at harvest. There are no offspring currently recorded for this variety.