Apple MAC
Modern
PLFhybrid
Pepe Le Fume
Top flavors
earthyspicycitrus
Terpenes
CalmingEnergizing
Pepe Le Fume effects are mostly calming.
Pepe Le Fume
Terpene Profile
Synergies (+) and conflicts (−) are relative to each other within this profile.
myrcene ~60%caryophyllene ~28%limonene ~12%
| Terpene | Share | Character | Likely role |
|---|---|---|---|
| myrcene | ~60% | earthy | relaxing · solo |
| caryophyllene | ~28% | spicy | relaxing · social |
| limonene | ~12% | citrus | social · creative |
Research notes below describe isolated terpene mechanisms and early findings. They do not guarantee effects from this strain and are not medical advice.
Russo 2011: naloxone-sensitive analgesia, potentiates barbiturate sleep; dominant sedating terpenoid; blocks hepatic carcinogenesis by aflatoxin.
~28%
spicy
●●○○
Russo 2011: only terpene that is a selective full CB2 agonist (100 nM); Gertsch et al. 2008: acts as dietary cannabinoid; unique anti-inflammatory and gastric cytoprotective properties.
Russo 2011: increases serotonin in prefrontal cortex + dopamine in hippocampus via 5-HT1A; Johns Hopkins 2024: significantly reduced anxiety vs THC alone.
Effects
Reported effects — derived from terpene chemistry and cannabinoid profile.
◎
relaxed
eveningPrimary endpoint of myrcene+linalool sedating combinations; GABA modulation is the dominant mechanistic driver.
◉
happy
anytime△
uplifted
morningLimonene anxiolytic/antidepressant via serotonin elevation in prefrontal cortex (Russo 2011); mood improvement without full euphoria; key for balanced-1-1 profiles.
Genetic Profile
Balanced Hybrid
■ Indica 50%■ Sativa 50%
Equal indica and sativa genetics. Balanced body and mind effects.
THC-Dominant
High THC, trace CBD. Psychoactive. Full CB1 agonism — euphoria, appetite, analgesia.
Genealogy
Parentage, ancestry, and genetic relatives of Pepe Le Fume.
Composite Traits
Where to buy Pepe Le Fume
No verified dispensaries on file — find it on Leafly.
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What would Pepe Le Fume × ? produce?
Predict the terpene profile, effects, and growing traits of a cross. Our gene weaver engine votes on dominant traits from both parents.
Build a cross with Pepe Le Fume →Similar strains
Same primary terpene with overlapping effects.
Frequently Asked Questions
Is Pepe Le Fume indica or sativa?
Pepe Le Fume is modeled here as a balanced hybrid (equal indica and sativa genetics).
What terpene is dominant in Pepe Le Fume?
Myrcene is shown as the dominant terpene at approximately ~60%. Caryophyllene follows as the secondary terpene.
Is Pepe Le Fume good for daytime use?
Pepe Le Fume is versatile and works across different times of day depending on dose and individual response.
How accurate is this data?
See the "Data confidence" card in the sidebar. Terpene profiles and effects are chemistry-informed estimates — individual responses depend on phenotype, source, and personal chemistry.