Permanent Marker is a modern hybrid-indica strain developed through the crossbreeding of Biscotti, Jealousy, and Sunset Sherbet. Cultivation of this strain is considered difficult and requires an indoor environment to reach its full potential, with a flowering period that typically spans 63 days before offering a medium yield. The strain has served as a prolific foundation for modern genetics, with notable offspring including Alien Paya, All Starz, Black Rainbow, Black Soap, Bucket List, Candi Chrome, Candy Blast, Chad Special, Chad's Revenge, Creamy & Minty, Dry Erase Marker, and Gas Mark 10.

The sensory profile of Permanent Marker is defined by a complex terpene hierarchy, led by limonene, caryophyllene, and linalool. These are supported by a diverse minor terpene array consisting of pinene, beta-pinene, humulene, bisabolol, ocimene, nerolidol, myrcene, caryophyllene-oxide, camphene, valencene, borneol, terpinolene, geraniol, isopulegol, and sabinene. This chemical composition results in an aromatic experience reflecting the distinct contributions of these specific aromatic compounds.

As a THC-dominant cultivar, Permanent Marker is categorized by its capacity to produce relaxed, euphoric, calm, and sleepy effects. These qualities make it a frequent selection for consumers managing stress, anxiety, or seeking assistance with sleep. Its influence on the current cannabis landscape is evidenced by its widespread use in breeding programs, establishing it as a significant contributor to the modern gene pool.