Querkle is classified as a modern hybrid-indica strain with an undocumented lineage. It requires a moderate level of expertise from cultivators, who can expect a high yield from this variety when grown in both indoor and outdoor environments. The plant reaches maturity relatively quickly, finishing its flowering stage in approximately 56 days.

The chemical profile of Querkle is defined by a terpene sequence dominated by myrcene, which is supported by secondary notes of caryophyllene and tertiary traces of pinene. This specific terpene composition influences its distinct sensory profile. As a THC-dominant cultivar, the strain provides a consistent experience characterized by the interplay of these three compounds.

In terms of effects, Querkle is reported to induce a state of relaxed, calm focus in consumers. It is frequently sought out by those looking to address pain, stress, or challenges with sleep. Beyond its primary applications, the strain is a significant contributor to the modern gene pool, serving as a parent to numerous varieties including Smoke Alarm, .508, Alchemy, B.S., Black Dahlia, Cheese Quake, Deep Purple Querkle, Dragon's Queen, Grape Inferno, Heavy Duty Querkle, Hell Stone, and Hurkle.