A.M.S.
Modern
SMhybrid
Santa Maria
Top flavors
earthyspicycitrus
Terpenes
CalmingEnergizing
Santa Maria effects are mostly calming.
Santa Maria
Santa Maria is a modern hybrid strain with an undocumented lineage. Known for its versatile cultivation profile, the plant reaches maturity after a 63-day flowering period. It is considered to have a moderate growing difficulty and serves as a high-yielding variety suited for both indoor and outdoor environments.
The terpene profile of Santa Maria is led by myrcene, followed by caryophyllene and limonene. This specific arrangement of terpenes dictates the strain’s chemical character, influencing both the aromatic qualities and the sensory experience provided to the user.
Users of this THC-dominant strain report a range of effects including feelings of relaxation, happiness, and an uplifted mood. Its therapeutic profile makes it a candidate for those managing stress, pain, or difficulties with sleep. The genetic legacy of Santa Maria is extensive, as it has served as a parent to numerous varieties including Auto Frosty Bud, Bubblegum XL, Crystal Ryder, Lucky Queen, Lungomar, Mantis, Smurf, Speed Ryder #2, Sugar Mango Ryder, and Sweet Coffee Ryder.
Terpene Profile
Synergies (+) and conflicts (−) are relative to each other within this profile.
myrcene ~60%caryophyllene ~28%limonene ~12%
| Terpene | Share | Character | Likely role |
|---|---|---|---|
| myrcene | ~60% | earthy | relaxing · solo |
| caryophyllene | ~28% | spicy | relaxing · social |
| limonene | ~12% | citrus | social · creative |
Research notes below describe isolated terpene mechanisms and early findings. They do not guarantee effects from this strain and are not medical advice.
Russo 2011: naloxone-sensitive analgesia, potentiates barbiturate sleep; dominant sedating terpenoid; blocks hepatic carcinogenesis by aflatoxin.
~28%
spicy
●●○○
Russo 2011: only terpene that is a selective full CB2 agonist (100 nM); Gertsch et al. 2008: acts as dietary cannabinoid; unique anti-inflammatory and gastric cytoprotective properties.
Russo 2011: increases serotonin in prefrontal cortex + dopamine in hippocampus via 5-HT1A; Johns Hopkins 2024: significantly reduced anxiety vs THC alone.
Effects
Reported effects — derived from terpene chemistry and cannabinoid profile.
◎
relaxed
eveningPrimary endpoint of myrcene+linalool sedating combinations; GABA modulation is the dominant mechanistic driver.
◉
happy
anytime△
uplifted
morningLimonene anxiolytic/antidepressant via serotonin elevation in prefrontal cortex (Russo 2011); mood improvement without full euphoria; key for balanced-1-1 profiles.
Genetic Profile
Balanced Hybrid
■ Indica 50%■ Sativa 50%
Equal indica and sativa genetics. Balanced body and mind effects.
THC-Dominant
High THC, trace CBD. Psychoactive. Full CB1 agonism — euphoria, appetite, analgesia.
Genealogy
Parent data not yet recorded for Santa Maria.
Composite Traits
Where to buy Santa Maria
No verified dispensaries on file — find it on Leafly.
Dispensary Locator
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Community Reviews
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What would Santa Maria × ? produce?
Predict the terpene profile, effects, and growing traits of a cross. Our gene weaver engine votes on dominant traits from both parents.
Build a cross with Santa Maria →Similar strains
Same primary terpene with overlapping effects.
Frequently Asked Questions
Is Santa Maria indica or sativa?
Santa Maria is modeled here as a balanced hybrid (equal indica and sativa genetics).
What terpene is dominant in Santa Maria?
Myrcene is shown as the dominant terpene at approximately ~60%. Caryophyllene follows as the secondary terpene.
Is Santa Maria good for daytime use?
Santa Maria is versatile and works across different times of day depending on dose and individual response.
How accurate is this data?
See the "Data confidence" card in the sidebar. Terpene profiles and effects are chemistry-informed estimates — individual responses depend on phenotype, source, and personal chemistry.