Third Leg
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Terpenes
Third Leg effects are mostly calming.
Third Leg
Third Leg is a modern hybrid strain with an undocumented lineage. The variety is characterized by a moderate cultivation difficulty and adapts well to both indoor and outdoor environments. Growers can expect a high yield from this plant, which reaches maturity after a 63-day flowering period.
The sensory profile of this cultivar is defined by a terpene composition led by myrcene, followed by caryophyllene and limonene. This specific arrangement of terpenes dictates the nuanced aromatic and flavor qualities of the flower. These compounds contribute to a distinct profile that balances the earthy, grounding influence of the dominant myrcene with the spice of caryophyllene and the bright notes of limonene.
As a THC-dominant hybrid, Third Leg induces effects that are primarily relaxed, happy, and uplifted. These properties make the strain a suitable choice for users seeking relief from stress and pain, or aid with sleep. The influence of Third Leg extends to its notable genetic legacy, having been used to develop a diverse list of offspring including 631, Animal Orgy, Cherry Salami 91, Glue Pops, Ridge Town, Salami Brittle, Stanky Leg, and Sweet Meat.
Terpene Profile
Synergies (+) and conflicts (−) are relative to each other within this profile.
| Terpene | Share | Character | Likely role |
|---|---|---|---|
| myrcene | ~60% | earthy | relaxing · solo |
| caryophyllene | ~28% | spicy | relaxing · social |
| limonene | ~12% | citrus | social · creative |
Research notes below describe isolated terpene mechanisms and early findings. They do not guarantee effects from this strain and are not medical advice.
Russo 2011: naloxone-sensitive analgesia, potentiates barbiturate sleep; dominant sedating terpenoid; blocks hepatic carcinogenesis by aflatoxin.
~28%
spicy
●●○○
Russo 2011: only terpene that is a selective full CB2 agonist (100 nM); Gertsch et al. 2008: acts as dietary cannabinoid; unique anti-inflammatory and gastric cytoprotective properties.
Russo 2011: increases serotonin in prefrontal cortex + dopamine in hippocampus via 5-HT1A; Johns Hopkins 2024: significantly reduced anxiety vs THC alone.
Effects
Reported effects — derived from terpene chemistry and cannabinoid profile.
relaxed
eveningPrimary endpoint of myrcene+linalool sedating combinations; GABA modulation is the dominant mechanistic driver.
happy
anytimeuplifted
morningLimonene anxiolytic/antidepressant via serotonin elevation in prefrontal cortex (Russo 2011); mood improvement without full euphoria; key for balanced-1-1 profiles.
Genetic Profile
Balanced Hybrid
Equal indica and sativa genetics. Balanced body and mind effects.
THC-Dominant
High THC, trace CBD. Psychoactive. Full CB1 agonism — euphoria, appetite, analgesia.
Genealogy
Parent data not yet recorded for Third Leg.
Composite Traits
Where to buy Third Leg
No verified dispensaries on file — find it on Leafly.
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What would Third Leg × ? produce?
Predict the terpene profile, effects, and growing traits of a cross. Our gene weaver engine votes on dominant traits from both parents.
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Frequently Asked Questions
Is Third Leg indica or sativa?
Third Leg is modeled here as a balanced hybrid (equal indica and sativa genetics).
What terpene is dominant in Third Leg?
Myrcene is shown as the dominant terpene at approximately ~60%. Caryophyllene follows as the secondary terpene.
Is Third Leg good for daytime use?
Third Leg is versatile and works across different times of day depending on dose and individual response.
How accurate is this data?
See the "Data confidence" card in the sidebar. Terpene profiles and effects are chemistry-informed estimates — individual responses depend on phenotype, source, and personal chemistry.