Wedding Cake
Modern
Dhybrid-indica
Do-Si-Dos
22.8%
THC
0.06%
CBD
Top flavors
spicyearthycitrus
Terpenes
CalmingEnergizing
Do-Si-Dos has balanced effects.
Low THCHigh THC
Do-Si-Dos potency is average.
Do-Si-Dos
22.8%
THC
0.06%
CBD
Top flavors
spicyearthycitrus
Terpenes
CalmingEnergizing
Do-Si-Dos has balanced effects.
Low THCHigh THC
Do-Si-Dos potency is average.
Do-Si-Dos is a classic hybrid-indica resulting from the crossing of Girl Scout Cookies and Gelato genetics. This lineage is formed through the combination of two prominent contemporary cultivars. Growers should anticipate a moderate difficulty level when cultivating this strain indoors.
The aromatic and flavor profile of Do-Si-Dos is driven by caryophyllene, humulene, limonene, linalool, bisabolol, terpinolene, myrcene, beta-pinene, and pinene. This terpene chemistry contributes to its characteristic sensory experience, which manifests as a complex interplay between these compounds.
This THC-dominant strain, testing at 22.8% THC and 0.06% CBD, is primarily utilized by those seeking to manage stress, anxiety, or sleep, as its effects are consistently reported as relaxed, happy, and sleepy. The genetic footprint of Do-Si-Dos remains significant within the industry, as evidenced by its list of offspring, including Animal Cookies x Do-si-dos, Sherbet-Z, Bernside, Do-Si-Dos x Birthday Cake x Strawbanana Cream, Savage Hulk, Peanut Butter Soda, Bag O' Dosi, Black Truffle Gelato, Cage Dancer, Certified Banger, ChemPie, and Cherry Do-Si-Dos.
Terpene Profile
Synergies (+) and conflicts (−) are relative to each other within this profile.
caryophyllene ~60%humulene ~28%limonene ~12%
| Terpene | Share | Character | Likely role |
|---|---|---|---|
| caryophyllene | ~60% | spicy | relaxing · social |
| humulene | ~28% | earthy | focus · solo |
| limonene | ~12% | citrus | social · creative |
Research notes below describe isolated terpene mechanisms and early findings. They do not guarantee effects from this strain and are not medical advice.
~60%
spicy
●●○○
Russo 2011: only terpene that is a selective full CB2 agonist (100 nM); Gertsch et al. 2008: acts as dietary cannabinoid; unique anti-inflammatory and gastric cytoprotective properties.
PMC11060501: opioid-independent antinociception; appetite suppression (anorectic); NF-κB dual-pathway synergy with caryophyllene.
Russo 2011: increases serotonin in prefrontal cortex + dopamine in hippocampus via 5-HT1A; Johns Hopkins 2024: significantly reduced anxiety vs THC alone.
Effects
Reported effects — derived from terpene chemistry and cannabinoid profile.
◎
relaxed
eveningPrimary endpoint of myrcene+linalool sedating combinations; GABA modulation is the dominant mechanistic driver.
◑
sleepy
eveningMyrcene potentiates barbiturate sleep (Russo 2011); CBN 2024 RCT reduces nighttime awakenings at 20 mg; nerolidol+myrcene+linalool GABAergic compounded effect.
◉
happy
anytimeGenetic Profile
Indica-dominant
■ Indica 70%■ Sativa 30%
Primarily indica with sativa influence. Relaxing body with some cerebral lift.
THC-Dominant
High THC, trace CBD. Psychoactive. Full CB1 agonism — euphoria, appetite, analgesia.
Archive Seed Bank's GSC × Face Off OG cross; dense frosty buds with sweet floral-earth aroma and powerful sedative effects.
Genealogy
Parentage, ancestry, and genetic relatives of Do-Si-Dos.
Ancestry
Great-grandparents
Chemdawg
caryophyllene· creative· relaxed
Hindu KushLandrace
camphene· relaxed· sleepy
Pink Panties
pinene· relaxed· focused
Grandparents
Durban PoisonLandrace
terpinolene· energetic· uplifted
Girl Scout Cookies
caryophyllene· relaxed· creative
OG Kush
limonene· relaxed· creative
Sunset Sherbet
caryophyllene· relaxed· uplifted
▾
Siblings
Share parents girl scout cookies / gelato
BiscottimyrceneGusherscaryophylleneWedding CakecaryophylleneApples and BananasmyrceneGelato CookiescaryophylleneRuderalismyrceneAnimal CookieslimoneneIce Cream CakelimoneneRuntzlimoneneCookies and CreamlimoneneGelatolimoneneAuto GelatocaryophylleneAuto GSCcaryophylleneBanana IzozkicaryophylleneBanana Soft ServelimoneneBig Body GelaticaryophylleneBizcochocaryophylleneBlack Do-latocaryophylleneBubba SlushcaryophylleneCheetah PisscaryophylleneCherry LimeadecaryophylleneDying DreamingmyrceneGandalf's Wizard SleevecaryophylleneGelato PoplimoneneJaffalatocaryophylleneJealousylimoneneJet Fuel GelatocaryophyllenePapaya SorbetcaryophyllenePapayatoncaryophyllenePink Runtzlimonene
Offspring — 30 strains bred from Do-Si-Dos
2y2caryophylleneAca-Dos DelightcaryophylleneAj's cookiescaryophylleneAlaskan Do-Si-DoscaryophylleneBag O' DosicaryophylleneBernsidecaryophylleneBiohazardcaryophylleneBlack FruitcaryophylleneBlack Truffle GelatocaryophylleneBubblewrapcaryophylleneBurnt OrangecaryophylleneCactidocaryophylleneCage DancercaryophylleneCaloosahatchee KushcaryophylleneCandy HousecaryophylleneCannaradosicaryophylleneCertified BangercaryophylleneChemPiecaryophylleneCherry CreamcaryophylleneCherry Do-Si-DoscaryophylleneCherry DubyascaryophylleneCitrus RushcaryophylleneCookielatocaryophylleneCrip WalkcaryophylleneCrippy KillercaryophylleneCypress BreathcaryophylleneDO-GcaryophylleneDaiquiri OGcaryophylleneDaisy CuttercaryophylleneDazed N' Confuzedcaryophyllene
Composite Traits
Where to buy Do-Si-Dos
No verified dispensaries on file — find it on Leafly.
Dispensary Locator
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Community Reviews
★★★★★4.0 · 2 reviews
★★★★★Too much couch lock for my morning
11 May 2026Do-Si-Dos tasted decent earthy and sweet but man, it put me on my couch HARD. I made the mistake of hitting it before my morning coffee. My head buzz felt good but my body was stuck.
★★★★★Do-Si-Dos is my sleep hack
21 Apr 2026Yo, this Do-Si-Dos hit so good after a long day. It really melts away all the stress and just puts me in a chill mood, heavy body high always for sure. My insomnia doesn't stand a chance, I get proper sleep finally.
⊕
What would Do-Si-Dos × ? produce?
Predict the terpene profile, effects, and growing traits of a cross. Our gene weaver engine votes on dominant traits from both parents.
Build a cross with Do-Si-Dos →Similar strains
Same primary terpene with overlapping effects.
Frequently Asked Questions
Is Do-Si-Dos indica or sativa?
Do-Si-Dos is modeled here as a indica-dominant (primarily indica with sativa influence).
What terpene is dominant in Do-Si-Dos?
Caryophyllene is shown as the dominant terpene at approximately ~60%. Humulene follows as the secondary terpene.
Is Do-Si-Dos good for daytime use?
Do-Si-Dos is versatile and works across different times of day depending on dose and individual response.
How accurate is this data?
See the "Data confidence" card in the sidebar. Terpene profiles and effects are chemistry-informed estimates — individual responses depend on phenotype, source, and personal chemistry.