D#hybrid-indica
Hybrid-IndicaModernTHC-Dominantafternoon

Do-Si-Dos #18

17.8%

THC

Top flavors

spicyearthycitrus
CalmingEnergizing

Do-Si-Dos #18 has balanced effects.

Low THCHigh THC

Do-Si-Dos #18 potency is average.

Do-Si-Dos #18 is a modern hybrid-indica variety derived directly from parent genetics of Do-Si-Dos. Cultivators can expect a flowering period of 70 days, with the strain demonstrating a moderate level of cultivation difficulty. It is versatile enough to be grown in both indoor and outdoor environments, capable of producing high yields. The strain has established a foundational role in current breeding programs, serving as the genetic starting point for notable offspring such as Berry Apocalypse, Bronze 56k, Bubba Diagonal x Do Si Dos #18, and Sherb Dosi #8 x Dosidos #18.

The biochemical profile of Do-Si-Dos #18 is anchored by a complex arrangement of terpenes, led by dominant caryophyllene and supported by myrcene, limonene, and linalool. This primary aromatic structure is further nuanced by the presence of humulene, bisabolol, beta-pinene, and pinene. These compounds work in tandem to define the strain’s sensory signature, providing a distinct chemical tapestry that distinguishes the cultivar from others within the modern hybrid-indica classification.

Patients and users primarily utilize this THC-dominant strain to address concerns regarding pain, stress, and sleep. Its physiological effects are characterized by a pronounced sense of relaxation and calm, while simultaneously maintaining a state of mental focus. By combining these therapeutic use cases with its high-yielding cultivation profile, Do-Si-Dos #18 remains a functional tool for both home and professional growers who prioritize specific, consistent medicinal outcomes alongside substantial production volume.

Terpene Profile

Synergies (+) and conflicts (−) are relative to each other within this profile.

caryophyllene ~60%myrcene ~28%limonene ~12%
TerpeneShare
caryophyllene~60%
myrcene~28%
limonene~12%

Research notes below describe isolated terpene mechanisms and early findings. They do not guarantee effects from this strain and are not medical advice.

~60%

spicy

●●○○

Russo 2011: only terpene that is a selective full CB2 agonist (100 nM); Gertsch et al. 2008: acts as dietary cannabinoid; unique anti-inflammatory and gastric cytoprotective properties.

~28%

earthy

●●●○

Russo 2011: naloxone-sensitive analgesia, potentiates barbiturate sleep; dominant sedating terpenoid; blocks hepatic carcinogenesis by aflatoxin.

~12%

citrus

●●○○

Russo 2011: increases serotonin in prefrontal cortex + dopamine in hippocampus via 5-HT1A; Johns Hopkins 2024: significantly reduced anxiety vs THC alone.

Effects

Reported effects — derived from terpene chemistry and cannabinoid profile.

Genetic Profile

Indica-dominant

■ Indica 70%■ Sativa 30%

Primarily indica with sativa influence. Relaxing body with some cerebral lift.

THC-Dominant

High THC, trace CBD. Psychoactive. Full CB1 agonism — euphoria, appetite, analgesia.

Genealogy

Parentage, ancestry, and genetic relatives of Do-Si-Dos #18.

Composite Traits

Use caution if

appetite-boostdaytime-productivitymorning-use

Where to buy Do-Si-Dos #18

No verified dispensaries on file — find it on Leafly.

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What would Do-Si-Dos #18 × ? produce?

Predict the terpene profile, effects, and growing traits of a cross. Our gene weaver engine votes on dominant traits from both parents.

Build a cross with Do-Si-Dos #18

Similar strains

Same primary terpene with overlapping effects.

Frequently Asked Questions

Is Do-Si-Dos #18 indica or sativa?

Do-Si-Dos #18 is modeled here as a indica-dominant (primarily indica with sativa influence).

What terpene is dominant in Do-Si-Dos #18?

Caryophyllene is shown as the dominant terpene at approximately ~60%. Myrcene follows as the secondary terpene.

Is Do-Si-Dos #18 good for daytime use?

Do-Si-Dos #18 is versatile and works across different times of day depending on dose and individual response.

How accurate is this data?

See the "Data confidence" card in the sidebar. Terpene profiles and effects are chemistry-informed estimates — individual responses depend on phenotype, source, and personal chemistry.